Ariessence pure PDGF+

• Injected anywhere into the skin, especially for a regenerative under-eye treatment targeting darkness, elasticity, and fine lines.
• Applied topically after SkinPen microneedling and Tixel, with benefits including improvement of the texture of the skin, reduction of lines, pore size, wrinkles and scarring, brighten complexion, and reduce downtime.
  
  

Time to allow: 30-45 minutes

Before
If you are prone to cold sores, take medication prior. Avoid blood thinners 3 days prior.

During
Treatments are generally well-tolerated with minimal risk for adverse effects. Common side effects include temporary redness, swelling, or slight discomfort, which resolve quickly.

After
You may experience mild redness, swelling, or sensitivity immediately after the procedure, but these side effects usually subside within 24 to 48 hours with daily activities resumed the day after treatment. Most notice an improvement in skin texture and hydration within a few days of treatment. However, the most significant results, such as reduced wrinkles and improved firmness, typically become visible after 4 to 8 weeks as collagen production increases. Continued improvements can be seen for several months post-treatment.

Follow Up
For optimal results, multiple treatments may be recommended. Many patients receive a series of 3 treatments spaced 4 to 6 weeks apart, with maintenance treatments as needed. Results can last anywhere from 6 months to a year, depending on your skin condition and maintenance routine. Regular follow-up treatments and a good skincare regimen can help prolong the benefits.

What exactly is PDGF in general?
Platelet-derived growth factors (PDGF) are naturally occurring proteins in the body known for their critical role in cellular growth, tissue repair, and wound healing. By promoting the proliferation of fibroblasts and endothelial cells, PDGF plays a key role in the production of collagen and elastin, the two essential components for maintaining youthful, healthy skin.
Pure PDGF+ utilizes a bioidentical, lab-derived form of PDGF that delivers consistent and highly effective results for various aesthetic treatments. The PDGF in Ariessence is produced using an FDA-approved manufacturing process that results in a sterile and pure version of PDGF with no mRNA or DNA in the product.

What is Ariessence pure PDGF+ made up of?
It contains 4 ingredients: water, sodium acetate, hyaluronic acid and sh-polypeptide-59 dimer.

Who is a good candidate?

• Those seeking to reduce fine lines, wrinkles, or scars.
• Individuals with dull, uneven skin tone or texture.
• Patients looking to enhance the results of SkinPen microneedling or Tixel treatments.
• People who want a non-invasive alternative to PRP/PRF treatments.
• Those who want a natural alternative to tear trough dermal filler.
• People looking to boost the strength and growth of hair on the scalp.

How does pure PDGF+ work with SkinPen microneedling and Tixel?
During these treatments, a controlled injury happens in the top layers of the skin, triggering the body's natural healing response. Applying Ariessence pure PDGF+ enhances this response by providing concentrated growth factors that accelerate the production of collagen, elastin and hydration. This results in firmer, smoother skin with improved texture and reduced signs of aging.

How does pure PDGF+ work for under the eyes compared to dermal filler?
Pure PDGF+ works for under-eye areas by stimulating natural skin regeneration and collagen production through its growth factor technology, helping to reduce puffiness, dark circles, and fine lines over time. Unlike dermal fillers, which provide instant volume by directly injecting substances to plump and smooth skin typically lasting a year, pure PDGF+ enhances the skin's ability to repair and renew itself over time, resulting in a more natural, long-term improvement in skin tone and texture. Initial volume is present and gradually decreases over the next few weeks while your body’s collagen and HA replaces it.

How is pure PDGF+ different from PRP and PRF?
Traditional PRP/PRF treatments require drawing your blood, isolating the platelet-rich plasma or fibrin by spinning the blood in a centrifuge, and then applying it to the skin. While PRP/PRF are both effective, the process can be time-consuming, invasive, inconsistent depending on your blood and health, and uncomfortable for some.
With pure PDGF+, you do not need to have your blood drawn. It is a synthesized or purified growth factor which makes the process simpler and less invasive compared to treatments like PRP or PRF. Instead of relying on your platelets, the product contains a laboratory-engineered version of PDGF. It delivers a more concentrated, consistent, and targeted approach, leading to faster and more noticeable results.


Which is more powerful, pure PDGF+, PRP or PRF?
When comparing the potency of PRP (Platelet-Rich Plasma), PRF (Platelet-Rich Fibrin), and pure PDGF+ (Platelet-Derived Growth Factor), pure PDGF+ stands out as the most powerful option. It provides 1,000 to 300,000 times the amount of growth factors compared to treatments like PRP, PRF, or exosomes. This high concentration of growth factors makes it a highly effective choice for enhancing skin rejuvenation, promoting faster healing, and achieving more significant improvements in aesthetic treatments.

Are there any human components in pure PDGF+?
No. The pure PDGF+ is made via cutting edge recombinant technology, a highly regulated sterile manufacturing process resulting in pharmaceutical grade PDGF with no human components. It is not derived from any human tissue or cells. There is no mRNA or DNA in the product. Every lot of PDGF meets exacting standards established during the FDA approval process for purity, potency and sterility. This process is similar to how many FDA approved biologic drugs are made today.